gpDB: a database of G-proteins and their interaction with GPCRs
Introduction Navigation Text Search Blast Search Pattern Search User Manual

gpDB::G-protein View
Entry 1 of 1 :: GPR0170 ::
CLASS Ggamma
FAMILY Ggamma
SUBFAMILY Ggamma
TYPE unclassified_Ggamma

Cross References:
UniProt P54406 EMBL AF291848 | Z67883
InterPro IPR015898 | IPR001770
PRODOM PD003783 WormPep K02A4.2
GENEID 181424
PRINTS PR00321 PFAM PF00631

Details:
NAME unclassified_Ggamma-Caenorhabditis elegans
DESCRIPTION Guanine nucleotide-binding protein subunit gamma precursor.
SPECIES Caenorhabditis elegans COMMON NAME - NCBI Taxonomy 6239
POST TRANSLATION MODIFICATIONS null GENE gpc-1 | K02A4.2
SEQUENCE
MENIKASTEQLCAEANIQRKKVSEVSKELLDFCEKNKTNDMLVSGPTDQHNPFQEKKSCS
VL
FRAGMENT NO
FUNCTION The beta and gamma chains are required for the GTPases activity, for replacement of GDP by GTP, and for G protein-s effector interaction
Effectors:
1EFF0167Calmodulin-Caenorhabditis elegans-1Inhibition of calmodulin kinase15251227
2EFF0168Calmodulin-Caenorhabditis elegans-2Inhibition of calmodulin kinase15251227
3EFF0382Kinase suppressor of Ras(KSR)-Caenorhabditis elegansSequestration of Gbeta/gamma15251227
4EFF0617Rac-Caenorhabditis elegans-1Stimulation,Recruitment to plasma membrane11099498 | 15251227
5EFF0618Rac-Caenorhabditis elegans-2Stimulation,Recruitment to plasma membrane11099498 | 15251227
6EFF0723Rho-Caenorhabditis elegansRecruitment to plasma membrane15251227
7EFF0982Tubulin-Caenorhabditis elegans-1Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
8EFF0983Tubulin-Caenorhabditis elegans-10Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
9EFF0984Tubulin-Caenorhabditis elegans-11Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
10EFF0985Tubulin-Caenorhabditis elegans-12Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
11EFF0986Tubulin-Caenorhabditis elegans-13Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
12EFF0987Tubulin-Caenorhabditis elegans-14Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
13EFF0988Tubulin-Caenorhabditis elegans-15Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
14EFF0989Tubulin-Caenorhabditis elegans-16Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
15EFF0990Tubulin-Caenorhabditis elegans-17Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
16EFF0991Tubulin-Caenorhabditis elegans-18Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
17EFF0992Tubulin-Caenorhabditis elegans-19Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
18EFF0993Tubulin-Caenorhabditis elegans-2Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
19EFF0994Tubulin-Caenorhabditis elegans-3Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
20EFF0995Tubulin-Caenorhabditis elegans-4Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
21EFF0996Tubulin-Caenorhabditis elegans-5Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
22EFF0997Tubulin-Caenorhabditis elegans-6Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
23EFF0998Tubulin-Caenorhabditis elegans-7Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
24EFF0999Tubulin-Caenorhabditis elegans-8Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
25EFF1000Tubulin-Caenorhabditis elegans-9Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086

Coupling with GPCRs:
No information




Designed for viewing with Internet Explorer 4 or above, Netscape 6 or above.
contact biodbbiol.uoa.gr
for comments, corrections and
data (sequence) submission.
athina University of Athens
Faculty of Biology
Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory