gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::G-protein View
Entry 1 of 1 :: GPR0153 ::
CLASS Gbeta
FAMILY Gbeta
SUBFAMILY Gbeta
TYPE Gbeta-2

Cross References:
UniProt Q20636 EMBL AF291847 | Z71263
InterPro IPR001632 | IPR015943 | IPR001680
PRODOM PD000018 WormPep F52A8.2
GENEID 172483
PRINTS PR00319 | PR00320 PFAM PF00400

Details:
NAME Gbeta-2-Caenorhabditis elegans
DESCRIPTION Guanine nucleotide-binding protein subunit beta-2.
SPECIES Caenorhabditis elegans COMMON NAME - NCBI Taxonomy 6239
POST TRANSLATION MODIFICATIONS null GENE gpb-2 | F52A8.2
SEQUENCE
MPENSQPTTTEKGSEYLEQLANEAEELRKKLDQERHKLNDIPIQQAAERLDVMGALGVKQ
RRILKGHVGKVLCMDWSLDKRHIVSSSQDGKVIVWDGFTTNKEHALTMPTTWVMACAFSP
SSQMIACGGLDNKCSVVPLSFEDDIIQKKRQVATHTSYMSCCTFLRSDNLILTGSGDSTC
AIWDVESGQLIQNFHGHTGDVFAIDVPKCDTGNTFISAGADKHSLVWDIRSGQCVQSFEG
HEADINTVRFHPNGDAFATGSDDATCRLFDLRADRQVCVYEKESILFPVNGVDFSLSGRI
LFAGYGDYRVGVWDSLKCARHSVLYGHENRISCLRTSPDGTAVCSASWDCTIRIWA
FRAGMENT NO
FUNCTION Guanine nucleotide-binding proteins (G proteins) ares involved as a modulator or transducer in various transmembranes signaling systems
Effectors:
1EFF0167Calmodulin-Caenorhabditis elegans-1Inhibition of calmodulin kinase15251227
2EFF0168Calmodulin-Caenorhabditis elegans-2Inhibition of calmodulin kinase15251227
3EFF0382Kinase suppressor of Ras(KSR)-Caenorhabditis elegansSequestration of Gbeta/gamma15251227
4EFF0617Rac-Caenorhabditis elegans-1Stimulation,Recruitment to plasma membrane11099498 | 15251227
5EFF0618Rac-Caenorhabditis elegans-2Stimulation,Recruitment to plasma membrane11099498 | 15251227
6EFF0723Rho-Caenorhabditis elegansRecruitment to plasma membrane15251227
7EFF0982Tubulin-Caenorhabditis elegans-1Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
8EFF0983Tubulin-Caenorhabditis elegans-10Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
9EFF0984Tubulin-Caenorhabditis elegans-11Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
10EFF0985Tubulin-Caenorhabditis elegans-12Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
11EFF0986Tubulin-Caenorhabditis elegans-13Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
12EFF0987Tubulin-Caenorhabditis elegans-14Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
13EFF0988Tubulin-Caenorhabditis elegans-15Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
14EFF0989Tubulin-Caenorhabditis elegans-16Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
15EFF0990Tubulin-Caenorhabditis elegans-17Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
16EFF0991Tubulin-Caenorhabditis elegans-18Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
17EFF0992Tubulin-Caenorhabditis elegans-19Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
18EFF0993Tubulin-Caenorhabditis elegans-2Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
19EFF0994Tubulin-Caenorhabditis elegans-3Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
20EFF0995Tubulin-Caenorhabditis elegans-4Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
21EFF0996Tubulin-Caenorhabditis elegans-5Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
22EFF0997Tubulin-Caenorhabditis elegans-6Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
23EFF0998Tubulin-Caenorhabditis elegans-7Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
24EFF0999Tubulin-Caenorhabditis elegans-8Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
25EFF1000Tubulin-Caenorhabditis elegans-9Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086

Coupling with GPCRs:
No information




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