gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::G-protein View
Entry 1 of 1 :: GPR0116 ::
CLASS Galpha
FAMILY Gs
SUBFAMILY Galpha-s
TYPE Galpha-s

Cross References:
UniProt P20354 | P20355 | Q2MGN1 | Q9W1F9 EMBL M23233 | M33998 | M33997 | M33998 | M33997 | AE013599 | AE013599 | AY058572
InterPro IPR001019 | IPR000367 | IPR011025
PRODOM PD000281 FlyBase FBgn0001123
GENEID 37805
PRINTS PR00318 | PR00443 PFAM PF00503

Details:
NAME Galpha-s-Drosophila melanogaster
DESCRIPTION Guanine nucleotide-binding protein G(s) subunit alpha (Adenylatecyclase-stimulating G alpha protein).
SPECIES Drosophila melanogaster COMMON NAME Fruit fly NCBI Taxonomy 7227
POST TRANSLATION MODIFICATIONS null GENE G-salpha60A | G-sa60A | CG2835
SEQUENCE 
MGCFGSPTSKQSDVNSEDSKSQKRRSDAISRQLQKDKQLYRATHRLLLLGAGESGKSTIV
KQMRILHVDGFSDSEKKQKIDDIKKNIRDAILTITGAMSTLNPPVALEKKENEPRVEYIQ
DYASSPDFNYPPEFYEHTEELWKDKGVLQTYERSNEYQLIDCAKYFLDRVSTIKNPNYTP
NEQDILRCRVLTSGIFETRFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVTACSS
YNMVLREDPTQNRLRESLDLFKSIWNNRWLRTISIILFLNKQDLLAEKIKAGKSKLSEYF
SEFNKYQTPIDTGDAIMESNDDPEVIRAKYFIRDEFLRISTASGDGKHYCYPHFTCAVDT
ENIKRVFNDCRDIIQRMHLRQYELL
 FRAGMENT NO
FUNCTION Guanine nucleotide-binding proteins (G proteins) ares involved as modulators or transducers in various transmembranes signaling systems
Effectors:
1EFF0847Src tyrosine kinase-Drosophila melanogaster-1Stimulation11007482 | 15251227 | 12209124
2EFF0848Src tyrosine kinase-Drosophila melanogaster-2Stimulation11007482 | 15251227 | 12209124
3EFF1041Tubulin-Drosophila melanogaster-1Stimulation of GTPase activity10224115 | 15251227 | 16380086
4EFF1042Tubulin-Drosophila melanogaster-10Stimulation of GTPase activity10224115 | 15251227 | 16380086
5EFF1045Tubulin-Drosophila melanogaster-13Stimulation of GTPase activity10224115 | 15251227 | 16380086
6EFF1047Tubulin-Drosophila melanogaster-14Stimulation of GTPase activity10224115 | 15251227 | 16380086
7EFF1050Tubulin-Drosophila melanogaster-12Stimulation of GTPase activity10224115 | 15251227 | 16380086
8EFF1051Tubulin-Drosophila melanogaster-11Stimulation of GTPase activity10224115 | 15251227 | 16380086
9EFF1052Tubulin-Drosophila melanogaster-2Stimulation of GTPase activity10224115 | 15251227 | 16380086
10EFF1053Tubulin-Drosophila melanogaster-3Stimulation of GTPase activity10224115 | 15251227 | 16380086
11EFF1054Tubulin-Drosophila melanogaster-4Stimulation of GTPase activity10224115 | 15251227 | 16380086
12EFF1055Tubulin-Drosophila melanogaster-5Stimulation of GTPase activity10224115 | 15251227 | 16380086
13EFF1056Tubulin-Drosophila melanogaster-6Stimulation of GTPase activity10224115 | 15251227 | 16380086
14EFF1057Tubulin-Drosophila melanogaster-7Stimulation of GTPase activity10224115 | 15251227 | 16380086
15EFF1058Tubulin-Drosophila melanogaster-8Stimulation of GTPase activity10224115 | 15251227 | 16380086
16EFF1059Tubulin-Drosophila melanogaster-9Stimulation of GTPase activity10224115 | 15251227 | 16380086

Coupling with GPCRs:
1GPCR0765DOPAMINE RECEPTOR_D1_Drosophila melanogaster-22144334



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