gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0894 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY GLYCOPROTEIN HORMONE RECEPTOR
SUBFAMILY TSH RECEPTOR

Cross References:
UniProt Q9I948 EMBL AB030955
InterPro IPR000276 | IPR002131 | IPR001611 | IPR002274 GPCRDB q9i948_9tele
PRINTS PR00373 | PR00237 | PR01145 PFAM PF00001 | PF00560

Details:
NAME GLYCOPROTEIN HORMONE RECEPTOR_TSH RECEPTOR_Oncorhynchus rhodurus-1
DESCRIPTION Thyrotropin receptor B.
SPECIES Oncorhynchus rhodurus COMMON NAME amago NCBI Taxonomy 41164
GENE sTSH-RB
SEQUENCE
MTENDRHSLQVITCALFTLVTLPIETLVDFESCPTVCDCSERKTYTISCFDIDVIPTFPA
STDTLWLLETRLNSVPGDVFSNLVNISRIYISVDLTLKRLERHSFYNLKKITHIEIRNAR
SLSYIDPEAFKNLPNLKYLGIFNTGLTIFPDLTNIHSDDMNFVLEITDHPYISEVPANSF
RGITNQVLTVMLYSNGFTDIQHHAFNGTKLDAVYLHRNRRLTRMDEDMFSGTVSGPMLLD
VSLTAVSSLPTAGLESLRELIARSAWNLKKLPPIKTFKHLTTADLTYPSHCCGFKNLKKK
RGYLEYIICNLTAFYDQQQKRSVGPLTVPSLQGDPTADTADQEPSEEGFRDGVFKDTQGD
PWRDFHSSLNYHVYFGGQPDDDVGFGEMLKNPQEDTSQNFDNRYDYVVCEEGEEVTCAPA
PDEFNPCEDIMGFSFLRVSVWFVSLLAVVGNMVVLLVLLTSHYKLSVSRFLMCHLAFADL
CMGIYLLLIASVDLHTKMEYYNHAIEWQTGPGCRLAGFLTVFASELSVYTLTMITLERWY
AITFALRLDRKLRLPHATAVMLAGWFFCLLLAMLPLVGVSSYQKVSICLPMDTKSTMAQV
YIISVLILNILAFLVICTCYVKIYCAVHNPYYCSGSKDTNIAKRMAILIFTDFLCMAPIS
FYAMSAVVDRPLITVSNSKILLVLFYPLNSCANPFLYAIFTKAFRGDIFILLSKVGLCQR
RAQLFRGQAVSSKGSSRVCQQVQGGKKRDTDRKRTGGPEEVPIHLQEYSGSGHTYIQLAS
QQPSPEESRSLET
FRAGMENT NO

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Dimerization:
HOMODIMER INFORMATION There is experimental evidence for homo-dimerization METHOD Fluorescence Resonance Energy Transfer (FRET) REFERENCES 12223484

Coupling with G-proteins:
No information


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athina University of Athens
Faculty of Biology
Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory