gpDB: a database of G-proteins and their interaction with GPCRs
Introduction Navigation Text Search Blast Search Pattern Search User Manual

gpDB::GPCR View
Entry 1 of 1 :: GPCR0760 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY DOPAMINE RECEPTOR
SUBFAMILY D1

Cross References:
UniProt P42291 EMBL U07865
InterPro IPR015694 | IPR000929 | IPR000276 GPCRDB drd1c_xenla
PRINTS PR00242 | PR00237 PFAM PF00001

Details:
NAME DOPAMINE RECEPTOR_D1_Xenopus laevis-1
DESCRIPTION D(1C) dopamine receptor.
SPECIES Xenopus laevis COMMON NAME African clawed frog NCBI Taxonomy 8355
GENE -
SEQUENCE
MENFSIFNVTVNVWHADLDVGNSDLSLRALTGLLLSLLILSTLLGNTLVCLAVIKFRHLR
SKVTNFFVISLAVSDLFVALLVMPWKAVTEVAGFWVFGDFCDTWVAFDIMCSTASILNLC
IISLDRYWAIASPFRYERKMTQRVAFIMIGVAWTLSILISFIPVQLSWHKSHEADEELNG
VNHTENCDSSLNRTYAISSSLISFYIPVVIMIGTYTRIYRIAQTQIRRISSLERAVEHAQ
RCSSRLSNENSLKTSFRKETKVLKTLSIIMGVFVFCWLPFFVLNCMIPFCHMNLPGQNEP
EPPCVSETTFNIFVWFGWANSSLNPVIYAFNADFRKAFTTILGCNRFCSSNNVEAVNFSN
ELVSYHHDTTFQKDIPVTFNNSHLPNVVDQDQEVLEGTCFDKVSVLSTSHGTRSQKNLHL
PAGVQFECEAEITLETITPFTSTGPLECLPQLVADEDRHYTTKLY
FRAGMENT NO

Homepage

Dimerization:
HOMODIMER INFORMATION There is experimental evidence for homo-dimerization METHOD Immunoprecipitation REFERENCES 9804783
HETERODIMER INFORMATION Forms heterodimers with Adenosine A1 Receptor. Heterodimerization results in altered D1 receptor signalling METHOD Immunoprecipitation REFERENCES 10890919

Coupling with G-proteins:
Family:Gs REFERENCES:2144334
1GPR0127Galpha-s-Xenopus laevis


Designed for viewing with Internet Explorer 4 or above, Netscape 6 or above.
contact biodbbiol.uoa.gr
for comments, corrections and
data (sequence) submission.
athina University of Athens
Faculty of Biology
Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory