gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0756 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY DOPAMINE RECEPTOR
SUBFAMILY D1

Cross References:
UniProt P42288 EMBL S67258
InterPro IPR015694 | IPR001413 | IPR000929 | IPR000276 GPCRDB drd1_didma
PRINTS PR00565 | PR00242 | PR00237 PFAM PF00001

Details:
NAME DOPAMINE RECEPTOR_D1_Didelphis marsupialis virginiana
DESCRIPTION D(1A) dopamine receptor.
SPECIES Didelphis marsupialis virginiana COMMON NAME North American opossum NCBI Taxonomy 9267
GENE DRD1
SEQUENCE
MPLNDTTMDRRGLVVERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNF
FVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDR
YWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLNWHKARPLSSPDGNVSSQDE
TMDNCDSSLSRTYAISSSLISFYIPVAIMIVTYTRIYRIAQKQIRRISALERAAVHAKNC
QNTTGNGANVECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCESD
LPSGETKPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPTANNA
IETVSINNNGAVFSSHHEPRGSISKDCNLVYLIPQAVTSRDPKKEEGGGSKPLEKTSPAL
SVILDYEVDLSLEKINPITQNGQHKT
FRAGMENT NO

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Dimerization:
HOMODIMER INFORMATION There is experimental evidence for homo-dimerization METHOD Immunoprecipitation REFERENCES 9804783
HETERODIMER INFORMATION Forms heterodimers with Adenosine A1 Receptor. Heterodimerization results in altered D1 receptor signalling METHOD Immunoprecipitation REFERENCES 10890919

Coupling with G-proteins:
No information


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athina University of Athens
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Biophysics
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