gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0710 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY CHEMOTACTIC PEPTIDE RECEPTOR
SUBFAMILY C5A

Cross References:
UniProt P79188 EMBL X97731
InterPro IPR002234 | IPR001274 | IPR000276 GPCRDB c5ar_macmu
PRINTS PR01104 | PR00426 | PR00237 PFAM PF00001

Details:
NAME CHEMOTACTIC PEPTIDE RECEPTOR_C5A_Macaca mulatta
DESCRIPTION C5a anaphylatoxin chemotactic receptor .
SPECIES Macaca mulatta COMMON NAME Rhesus macaque NCBI Taxonomy 9544
GENE C5AR1 | C5AR | C5R1
SEQUENCE
TPDYGHYDDKDTLDANTPVDKTSNTLRVPDILALVIFAVVFLVGVLRNALVVWVTAFEAK
RTINAIWFLNLAVADFLSCLALPILFTSIVQHHHWPFGGAACRILPSLILLNMYASILLL
ATISADRFLLVFNPIWCQNFRGAGLAWIACAVAWGLALLLTIPSFLYRVVREEYFPPKVL
CGVDHGHDKRRERAVAIARLVLGFVWPLLTLTMCYTFLLLRTWSRRATRSTKTLKVVVAV
VASFFIFWLPYQVTGMMMSFLEPSSPTFLLLKKLDSLCISFAYINCCINPIIYVVAGQGF
QGRLRKSLPSLLRNVLTEESMVRESKSFTRSTVDTMAQKT
FRAGMENT YES

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Dimerization:
HOMODIMER INFORMATION There is experimental evidence for homo-dimerization METHOD Fluorescence Resonance Energy Transfer (FRET) REFERENCES 12835318

Coupling with G-proteins:
No information


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athina University of Athens
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Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory