gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0708 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY CHEMOTACTIC PEPTIDE RECEPTOR
SUBFAMILY C5A

Cross References:
UniProt O70129 EMBL U86103
InterPro IPR002234 | IPR001274 | IPR000276 GPCRDB c5ar_cavpo
PRINTS PR01104 | PR00426 | PR00237 PFAM PF00001

Details:
NAME CHEMOTACTIC PEPTIDE RECEPTOR_C5A_Cavia porcellus
DESCRIPTION C5a anaphylatoxin chemotactic receptor (C5a-R) (C5aR) (CD88 antigen).
SPECIES Cavia porcellus COMMON NAME Guinea pig NCBI Taxonomy 10141
GENE C5AR1 | C5R1
SEQUENCE
MMVTVSYDYDYNSTFLPDGFVDNYVERLSFGDLVAVVIMVVVFLVGVPGNALVVWVTACE
ARRHINAIWFLNLAAADLLSCLALPILLVSTVHLNHWYFGDTACKVLPSLILLNMYTSIL
LLATISADRLLLVLSPIWCQRFRGGCLAWTACGLAWVLALLLSSPSFLYRRTHNEHFSFK
VYCVTDYGRDISKERAVALVRLLVGFIVPLITLTACYTFLLLRTWSRKATRSAKTVKVVV
AVVSSFFVFWLPYQVTGILLAWHSPNSATYRNTKALDAVCVAFAYINCCINPIIYVVAGH
GFQGRLLKSLPSVLRNVLTEESLDKRHQSFARSTVDTMPQKSESV
FRAGMENT NO

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Dimerization:
HOMODIMER INFORMATION There is experimental evidence for homo-dimerization METHOD Fluorescence Resonance Energy Transfer (FRET) REFERENCES 12835318

Coupling with G-proteins:
Family:Gi/o REFERENCES:7887933
1GPR0107Galpha-i3-Cavia porcellus
2GPR0216Galpha-i1-Cavia porcellus
3GPR0224Galpha-i2-Cavia porcellus


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athina University of Athens
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