gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0701 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY CHEMOKINE RECEPTOR (CX3C)
SUBFAMILY CXR1

Cross References:
UniProt P46094 EMBL L36149 | AY275469 | BC069075 | BC069589
InterPro IPR000276 | IPR005393 GPCRDB xcr1_human
GENEID 2829 MIM 600552
PRINTS PR00237 | PR01568 PFAM PF00001

Details:
NAME CHEMOKINE RECEPTOR (CX3C)_CXR1_Homo sapiens
DESCRIPTION Chemokine XC receptor 1 (XC chemokine receptor 1) (Lymphotactinreceptor) (G-protein coupled receptor 5).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE XCR1 | CCXCR1 | GPR5
SEQUENCE
MESSGNPESTTFFYYDLQSQPCENQAWVFATLATTVLYCLVFLLSLVGNSLVLWVLVKYE
SLESLTNIFILNLCLSDLVFACLLPVWISPYHWGWVLGDFLCKLLNMIFSISLYSSIFFL
TIMTIHRYLSVVSPLSTLRVPTLRCRVLVTMAVWVASILSSILDTIFHKVLSSGCDYSEL
TWYLTSVYQHNLFFLLSLGIILFCYVEILRTLFRSRSKRRHRTVKLIFAIVVAYFLSWGP
YNFTLFLQTLFRTQIIRSCEAKQQLEYALLICRNLAFSHCCFNPVLYVFVGVKFRTHLKH
VLRQFWFCRLQAPSPASIPHSPGAFAYEGASFY
FRAGMENT NO

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Coupling with G-proteins:
Family:Gi/o REFERENCES:9632725
1GPR0020Galpha-o1-Homo sapiens
2GPR0109Galpha-i3-Homo sapiens
3GPR0218Galpha-i1-Homo sapiens-1
4GPR0226Galpha-i2-Homo sapiens-2
5GPR0261Galpha-i1-Homo sapiens-2
6GPR0334Galpha-o-Homo sapiens
7GPR0365Galpha-i2-Homo sapiens-1


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athina University of Athens
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Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory