gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0612 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY CHEMOKINE RECEPTOR (CX3C)
SUBFAMILY CXCR1

Cross References:
UniProt P70612 EMBL U71089
InterPro IPR001277 | IPR000276 | IPR000174 GPCRDB cxcr1_rat
GENEID 54258
PRINTS PR00645 | PR00237 | PR00427 PFAM PF00001

Details:
NAME CHEMOKINE RECEPTOR (CX3C)_CXCR1_Rattus norvegicus
DESCRIPTION High affinity interleukin-8 receptor A (IL-8R A) (CXCR-1) (CD181antigen).
SPECIES Rattus norvegicus COMMON NAME Rat NCBI Taxonomy 10116
GENE Il8ra | Cxcr1
SEQUENCE
MAEAEYFIWIAPEGDFEEEFGNITRMLPTGEYFSPCKRVPMTNRQAVVVFYALVFLLSLL
GNSLVMLVILYRRRTRSVTDVYVLNLAIADLLFSLTLPFLAVSKWKGWIFGTPLCKMVSL
LKEVNFFSGILLLACISVDRYLAIVHATRTLTRKRYLVKFVCMGTWGLSLVLSLPFAIFR
QAYKPYRSGTVCYEVLGEATADLRITLRGLSHIFGFLLPLFIMLVCYGLTLRTLFKAHMR
QKRRAMWVIFAVVLVFLLCCLPYNLVLLSDTLLGAHLIQDTCERRNNIDQALYITEILGF
SHSCLNPVIYAFVGQSFRHEFLKILANLVHKEVLTHHSASFRTSLTTIY
FRAGMENT NO

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Scaffold:
TYPE beta-arrestin-1 - 2 REFERENCES 10973280

Coupling with G-proteins:
Family:Gi/o REFERENCES:9390561
1GPR0026Galpha-o-Rattus norvegicus
2GPR0111Galpha-i3-Rattus norvegicus
3GPR0221Galpha-i1-Rattus norvegicus
4GPR0229Galpha-i2-Rattus norvegicus


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athina University of Athens
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Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory