| Details: |
| NAME |
CHEMOKINE RECEPTOR (CC)_CCR2_Homo sapiens |
| DESCRIPTION |
C-C chemokine receptor type 2 (C-C CKR-2) (CC-CKR-2) (CCR-2) (CCR2)(Monocyte chemoattractant protein 1 receptor) (MCP-1-R) (CD192antigen). |
| SPECIES |
Homo sapiens |
COMMON NAME |
Human |
NCBI Taxonomy |
9606 |
| GENE |
CCR2 | CMKBR2 |
| SEQUENCE |
MLSTSRSRFIRNTNESGEEVTTFFDYDYGAPCHKFDVKQIGAQLLPPLYSLVFIFGFVGN
MLVVLILINCKKLKCLTDIYLLNLAISDLLFLITLPLWAHSAANEWVFGNAMCKLFTGLY
HIGYFGGIFFIILLTIDRYLAIVHAVFALKARTVTFGVVTSVITWLVAVFASVPGIIFTK
CQKEDSVYVCGPYFPRGWNNFHTIMRNILGLVLPLLIMVICYSGILKTLLRCRNEKKRHR
AVRVIFTIMIVYFLFWTPYNIVILLNTFQEFFGLSNCESTSQLDQATQVTETLGMTHCCI
NPIIYAFVGEKFRSLFHIALGCRIAPLQKPVCGGPGVRPGKNVKVTTQGLLDGRGKGKSI
GRAPEASLQDKEGA
|
FRAGMENT |
NO
|
|
|
|
|
Homepage
|
| Dimerization: |
| HOMODIMER INFORMATION |
There is experimental evidence for homo-dimerization
|
METHOD |
Immunoprecipitation
|
REFERENCES |
10097088
|
| HETERODIMER INFORMATION |
Forms heterodimers with Chemokine CCR5 Receptor. Dimerization increases the sensitivity and range of signalling pathways activated
|
METHOD |
Immunoprecipitation, Fluorescence Resonance Energy Transfer (FRET)
|
REFERENCES |
11350939
|
|
biol.uoa.gr
for comments, corrections and
data (sequence) submission.
