gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0478 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY CANNABINOID RECEPTOR
SUBFAMILY CB1

Cross References:
UniProt P21554 | Q13949 | Q495Z0 | Q4PLI4 | Q4VBM6 | Q5UB37 | Q9UNN0 EMBL X54937 | X81120 | X81121 | AY766182 | AF107262 | U73304 | DQ067455 | AY225225 | AL136096 | BC074811 | BC074812 | BC095513 | BC100968 | BC100969 | BC100970 | BC100971
InterPro IPR002230 | IPR000810 | IPR000276 PDB 1LVQ | 1LVR | 2B0Y GPCRDB cnr1_human
GENEID 1268 MIM 114610
PRINTS PR00522 | PR00362 | PR00237 PFAM PF00001

Details:
NAME CANNABINOID RECEPTOR_CB1_Homo sapiens-2
DESCRIPTION Cannabinoid receptor 1 (CB1) (CB-R) (CANN6).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE CNR1 | CNR
SEQUENCE 
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQE
KMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIA
VLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVF
HRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLM
WTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWK
AHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLL
AIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQ
PLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
 FRAGMENT NO

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Scaffold:
TYPE FAN( factor associated with neutral sphingomyelinase activation) REFERENCES 11306675

Coupling with G-proteins:
Family:Gi/o REFERENCES:2165569
1GPR0020Galpha-o1-Homo sapiens
2GPR0109Galpha-i3-Homo sapiens
3GPR0218Galpha-i1-Homo sapiens-1
4GPR0226Galpha-i2-Homo sapiens-2
5GPR0261Galpha-i1-Homo sapiens-2
6GPR0334Galpha-o-Homo sapiens
7GPR0365Galpha-i2-Homo sapiens-1

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athina University of Athens
 Faculty of Biology
 Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory