gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0045 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY 5-HYDROXYTRYPTAMINE RECEPTOR
SUBFAMILY 5-HT-1D

Cross References:
UniProt P49145 | O02823 EMBL Z50162 | U60825
InterPro IPR000505 | IPR002231 | IPR000276 GPCRDB 5ht1d_rabit
PRINTS PR00514 | PR01101 | PR00237 PFAM PF00001

Details:
NAME 5-HYDROXYTRYPTAMINE RECEPTOR_5-HT-1D_Oryctolagus cuniculus
DESCRIPTION 5-hydroxytryptamine receptor 1D (5-HT-1D) (Serotonin receptor 1D) (5-HT-1D-alpha).
SPECIES Oryctolagus cuniculus COMMON NAME Rabbit NCBI Taxonomy 9986
GENE HTR1D
SEQUENCE
MSPSNQSAEGLPQEAANRSLNATGTPEAWDPGTLQALKISLAVVLSIITVATVLSNTFVL
TTILLTRKLHTPANYLIGSLATTDLLVSILVMPISIAYTITHTWNFGQVLCDIWVSSDIT
CCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAVVWAISICISIPPLFWRQAK
AHEEVSDCLVNTSQISYTIYSTCGAFYIPSVLLIVLYGRIYMAARNRILNPPSLYGKRFT
TAHLITGSAGSSLCSLSPSLGEGHSHSAGSPLFFNPVRIKLADSVLERKRISAARERKAT
KTLGIILGAFIGCWLPFFVASLVLPICRDSCWMPPGLFDFFTWLGYLNSLINPIIYTVFN
EDFRQAFQRVIHFRKAF
FRAGMENT NO

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Dimerization:
HOMODIMER INFORMATION There is experimental evidence for homo-dimerization METHOD Immunoprecipitation REFERENCES 10452531
HETERODIMER INFORMATION Forms functional heterodimers when co-expressed with 5-HT-1B Receptor. METHOD Immunoprecipitation REFERENCES 10452531

Coupling with G-proteins:
No information


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