gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0441 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY ANGIOTENSIN RECEPTOR
SUBFAMILY AT2

Cross References:
UniProt Q9N0J0 EMBL AJ277986
InterPro IPR000147 | IPR000248 | IPR000276 GPCRDB q9n0j0_bovin
PRINTS PR00241 | PR00636 | PR00237 PFAM PF00001

Details:
NAME ANGIOTENSIN RECEPTOR_AT2_Bos taurus
DESCRIPTION Angiotensin receptor 2 .
SPECIES Bos taurus COMMON NAME Bovine NCBI Taxonomy 9913
GENE at2
SEQUENCE 
LATLPLWATYYSHRYDWLFGPVMCKLFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQ
RRNPWQASYIVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKY
 FRAGMENT YES

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Dimerization:
HETERODIMER INFORMATION Forms heterodimer with AT1 Receptor. After the dimerization the AT2 receptor antagonizes function of the AT1 receptor METHOD Immunoprecipitation REFERENCES 11507095

Coupling with G-proteins:
Family:Gi/o REFERENCES:8663053
1GPR0017Galpha-o1-Bos taurus
2GPR0219Galpha-i1-Bos taurus
3GPR0294Galpha-i2-Bos taurus-2
4GPR0295Galpha-i2-Bos taurus-1

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