gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0436 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY ANGIOTENSIN RECEPTOR
SUBFAMILY AT2

Cross References:
UniProt Q9Z0Z6 EMBL AF080066
InterPro IPR000147 | IPR000248 | IPR001186 | IPR000276 GPCRDB agtr2_merun
PRINTS PR00241 | PR00636 | PR00993 | PR00237 PFAM PF00001

Details:
NAME ANGIOTENSIN RECEPTOR_AT2_Meriones unguiculatus
DESCRIPTION Type-2 angiotensin II receptor (AT2).
SPECIES Meriones unguiculatus COMMON NAME Mongolian jird NCBI Taxonomy 10047
GENE AGTR2
SEQUENCE
MKDNFSFAATSRNITSSLPFVNLNMSGTNDLIFNCSHKPSDKHLEAIPVLYYLIFVIGFA
VNIIVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVF
GSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFY
FRDVRTIEYLGVNACVMAFPPEKYAQWSAGIALMKNVLGFIIPLIFIATCYFGIRKHLLK
TNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALSWMGIINSCEVMAVIDLAL
PFAILLGFTNSCVNPFLYCFVGNRFQQKLRSMFRVPITWLQGKRETMSCRKSSSLREMDT
FVS
FRAGMENT NO

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Dimerization:
HETERODIMER INFORMATION Forms heterodimer with AT1 Receptor. After the dimerization the AT2 receptor antagonizes function of the AT1 receptor METHOD Immunoprecipitation REFERENCES 11507095

Coupling with G-proteins:
No information


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athina University of Athens
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Biophysics
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Laboratory