gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0038 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY 5-HYDROXYTRYPTAMINE RECEPTOR
SUBFAMILY 5-HT-1D

Cross References:
UniProt P79748 EMBL X83865
InterPro IPR000505 | IPR002231 | IPR000276 GPCRDB 5ht1d_fugru
PRINTS PR00514 | PR01101 | PR00237 PFAM PF00001

Details:
NAME 5-HYDROXYTRYPTAMINE RECEPTOR_5-HT-1D_Fugu rubripes
DESCRIPTION 5-hydroxytryptamine receptor 1D (5-HT-1D) (Serotonin receptor 1D)(5HT1D) (F1D).
SPECIES Fugu rubripes COMMON NAME Japanese pufferfish NCBI Taxonomy 31033
GENE htr1d
SEQUENCE
MELDNNSLDYFSSNFTDIPSNTTVAHWTEATLLGLQISVSVVLAIVTLATMLSNAFVIAT
IFLTRKLHTPANFLIGSLAVTDMLVSILVMPISIVYTVSKTWSLGQIVCDIWLSSDITFC
TASILHLCVIALDRYWAITDALEYSKRRTMRRAAVMVAVVWVISISISMPPLFWRQAKAH
EELKECMVNTDQISYTLYSTFGAFYVPTVLLIILYGRIYVAARSRIFKTPSYSGKRFTTA
QLIQTSAGSSLCSLNSASNQEAHLHSGAGGEGGGSPLFVNSVKVKLADNVLERKRLCAAR
ERKATKTLGIILGAFIICWLPFFVVTLVWAICKECSFDPLLFDVFTWLGYLNSLINPVIY
TVFNDEFKQAFQKLIKFRR
FRAGMENT NO

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Dimerization:
HOMODIMER INFORMATION There is experimental evidence for homo-dimerization METHOD Immunoprecipitation REFERENCES 10452531
HETERODIMER INFORMATION Forms functional heterodimers when co-expressed with 5-HT-1B Receptor. METHOD Immunoprecipitation REFERENCES 10452531

Coupling with G-proteins:
No information


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athina University of Athens
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Biophysics
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