| Details: |
| NAME |
GABA RECEPTOR_GABA-B-R2_Rattus norvegicus |
| DESCRIPTION |
Gamma-aminobutyric acid type B receptor subunit 2 precursor (GABA-Breceptor 2) (GABA-B-R2) (Gb2) (GABABR2) (G-protein coupled receptor51). |
| SPECIES |
Rattus norvegicus |
COMMON NAME |
Rat |
NCBI Taxonomy |
10116 |
| GENE |
Gabbr2 | Gpr51 |
| SEQUENCE |
MASPPSSGQPRPPPPPPPPARLLLPLLLSLLLWLAPGAWGWTRGAPRPPPSSPPLSIMGL
MPLTKEVAKGSIGRGVLPAVELAIEQIRNESLLRPYFLDLRLYDTECDNAKGLKAFYDAI
KYGPNHLMVFGGVCPSVTSIIAESLQGWNLVQLSFAATTPVLADKKKYPYFFRTVPSDNA
VNPAILKLLKHFRWRRVGTLTQDVQRFSEVRNDLTGVLYGEDIEISDTESFSNDPCTSVK
KLKGNDVRIILGQFDQNMAAKVFCCAFEESMFGSKYQWIIPGWYEPAWWEQVHVEANSSR
CLRRSLLAAMEGYIGVDFEPLSSKQIKTISGKTPQQFEREYNSKRSGVGPSKFHGYAYDG
IWVIAKTLQRAMETLHASSRHQRIQDFNYTDHTLGKIILNAMNETNFFGVTGQVVFRNGE
RMGTIKFTQFQDSREVKVGEYNAVADTLEIINDTIRFQGSEPPKDKTIILEQLRKISLPL
YSILSALTILGMIMASAFLFFNIKNRNQKLIKMSSPYMNNLIILGGMLSYASIFLFGLDG
SFVSEKTFETLCTVRTWILTVGYTTAFGAMFAKTWRVHAIFKNVKMKKKIIKDQKLLVIV
GGMLLIDLCILICWQAVDPLRRTVERYSMEPDPAGRDISIRPLLEHCENTHMTIWLGIVY
AYKGLLMLFGCFLAWETRNVSIPALNDSKYIGMSVYNVGIMCIIGAAVSFLTRDQPNVQF
CIVALVIIFCSTITLCLVFVPKLITLRTNPDAATQNRRFQFTQNQKKEDSKTSTSVTSVN
QASTSRLEGLQSENHRLRMKITELDKDLEEVTMQLQDTPEKTTYIKQNHYQELNDILSLG
NFTESTDGGKAILKNHLDQNPQLQWNTTEPSRTCKDPIEDINSPEHIQRRLSLQLPILHH
AYLPSIGGVDASCVSPCVSPTASPRHRHVPPSFRVMVSGL
|
FRAGMENT |
NO
|
|
|
|
|
Homepage
|
| Dimerization: |
| HETERODIMER INFORMATION |
Forms heterodimers with GABA-B-R1 Receptors. Upon dimerization, GABA-B-R2 serves as a molecular chaperone for GABA-B-R1 and is required for full receptor function
|
METHOD |
Immunoprecipitation, functional reconstitution
|
REFERENCES |
9872315 | 9872317 | 9872316
|
| Scaffold: |
| TYPE |
Syntenin
|
REFERENCES |
11891216
|
| Coupling with G-proteins: |
| Family:Gi/o |
REFERENCES: | 9872315 | | 1 | GPR0026 | Galpha-o-Rattus norvegicus | | 2 | GPR0111 | Galpha-i3-Rattus norvegicus | | 3 | GPR0221 | Galpha-i1-Rattus norvegicus | | 4 | GPR0229 | Galpha-i2-Rattus norvegicus |
|
biol.uoa.gr
for comments, corrections and
data (sequence) submission.
