gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::GPCR View
Entry 1 of 1 :: GPCR2578 ::
CLASS CLASS B (SECRETIN LIKE)
FAMILY CALCITONIN, AMYLIN, CGRP, AND ADRENOMEDULIN RECEPTOR
SUBFAMILY CALCITONIN

Cross References:
UniProt P32214 | P32213 EMBL L14618 | L14617 | L13040 | L13041
InterPro IPR003287 | IPR001688 | IPR001879 | IPR000832 GPCRDB calcr_rat
PRINTS PR00361 | PR01350 | PR00249 PFAM PF00002 | PF02793

Details:
NAME CALCITONIN, AMYLIN, CGRP, AND ADRENOMEDULIN RECEPTOR_CALCITONIN_Rattus norvegicus
DESCRIPTION Calcitonin receptor precursor (CT-R) (C1A/C1B).
SPECIES Rattus norvegicus COMMON NAME Rat NCBI Taxonomy 10116
GENE Calcr
SEQUENCE
MRFLLLNRFTLLLLLLVSPTPVLQAPTNLTDSGLDQEPFLYLVGRKKLLDAQYKCYDRIQ
QLPPYEGEGPYCNRTWDGWMCWDDTPAGVMSYQHCPDYFPDFDPTEKVSKYCDENGEWFR
HPDSNRTWSNYTLCNAFTPDKLHNAYVLYYLALVGHSMSIAALIASMGIFLFFKNLSCQR
VTLHKNMFLTYILNSIIIIIHLVEVVPNGDLVRRDPMHIFHHNTYMWTMQWELSPPLPLS
AHEGKMDPHDSEVISCKILHFFHQYMMACNYFWMLCEGIYLHTLIVMAVFTEDQRLRWYY
LLGWGFPIVPTIIHAITRAVYYNDNCWLSTETHLLYIIHGPVMAALVVNFFFLLNIVRVL
VTKMRQTHEAEAYMYLKAVKATMVLVPLLGIQFVVFPWRPSNKVLGKIYDYLMHSLIHFQ
GFFVATIYCFCNHEVQVTLKRQWAQFKIQWSHRWGRRRRPTNRVVSAPRAVAFAEPGGLP
IYICHQEPRNPPVSNNEGEEGTEMIPMNVIQQDSSA
FRAGMENT NO

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Scaffold:
TYPE alpha-filamin/ABP280( actin binding protein 280) REFERENCES 12531889

Coupling with G-proteins:
Family:Gq/11 REFERENCES:8732687
1GPR0032Galpha-11-Rattus norvegicus
2GPR0242Galpha-q-Rattus norvegicus
Family:Gs REFERENCES:1331173
3GPR0124Galpha-s-Rattus norvegicus-2
4GPR0392Galpha-s-Rattus norvegicus-1


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athina University of Athens
Faculty of Biology
Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory