gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::GPCR View
Entry 1 of 1 :: GPCR2557 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY VASOPRESSIN AND OXYTOCIN RECEPTOR
SUBFAMILY OT

Cross References:
UniProt P56494 EMBL U82440
InterPro IPR000276 | IPR002062 | IPR001817 GPCRDB oxyr_macmu
GENEID 702048
PRINTS PR00237 | PR00665 | PR00896 PFAM PF00001

Details:
NAME VASOPRESSIN AND OXYTOCIN RECEPTOR_OT_Macaca mulatta
DESCRIPTION Oxytocin receptor (OT-R).
SPECIES Macaca mulatta COMMON NAME Rhesus macaque NCBI Taxonomy 9544
GENE OXTR
SEQUENCE
MEGELAANWSTEAVNSSAAPPGAEGNCTAGPPRRNEALARVEVAVLCLILFLALSGNACV
LLALRTTRHKHSRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYGPDLLCRLVKYLQV
VGMFASTYLLLLMSLDRCLAICQPLRSLRRRTDRLAVLATWLGCLVASAPQVHIFSLREV
ADGVFDCWAVFIQPWGPKAYITWITLAVYIVPVIVLAACYGLISFKIWQNLRLKTAAAAA
AEAPEGAAAGDGGRMALARVSSVKLISKAKIRTVKMTFIIVLAFIVCWTPFFFVQMWSVW
DANAPKEASAFIIVMLLASLNSCCNPWIYMLFTGHLFHELVQRFLCCSASYLKGNRLGET
STSKKSNSSSFVLSHRSSSQRSCSQPSTA
FRAGMENT NO

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Dimerization:
HOMODIMER INFORMATION There is experimental evidence for homo-dimerization METHOD Bioluminescence Resonance Energy Transfer (BRET) REFERENCES 12554793
HETERODIMER INFORMATION Forms functional heterodimers with V2 Receptors METHOD Bioluminescence Resonance Energy Transfer (BRET) REFERENCES 12554793
HETERODIMER INFORMATION Forms functional heterodimers with V1A Receptors METHOD Bioluminescence Resonance Energy Transfer (BRET) REFERENCES 12554793

Coupling with G-proteins:
Family:Gq/11 REFERENCES:1313946
1GPR0352Galpha-11-Macaca mulatta


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athina University of Athens
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