| Details: |
| NAME |
VASOPRESSIN AND OXYTOCIN RECEPTOR_OT_Rattus norvegicus |
| DESCRIPTION |
Oxytocin receptor (OT-R). |
| SPECIES |
Rattus norvegicus |
COMMON NAME |
Rat |
NCBI Taxonomy |
10116 |
| GENE |
Oxtr | Otr |
| SEQUENCE |
MEGTPAANWSVELDLGSGVPPGEEGNRTAGPPQRNEALARVEVAVLCLILFLALSGNACV
LLALRTTRHKHSRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYGPDLLCRLVKYLQV
VGMFASTYLLLLMSLDRCLAICQPLRSLRRRTDRLAVLGTWLGCLVASAPQVHIFSLREV
ADGVFDCWAVFIQPWGPKAYVTWITLAVYIVPVIVLAACYGLISFKIWQNLRLKTAAAAA
AAEGNDAAGGAGRAALARVSSVKLISKAKIRTVKMTFIIVLAFIVCWTPFFFVQMWSVWD
VNAPKEASAFIIAMLLASLNSCCNPWIYMLFTGHLFHELVQRFFCCSARYLKGSRPGETS
VSKKSNSSTFVLSRRSSSQRSCSQPSSA
|
FRAGMENT |
NO
|
|
|
|
|
Homepage
|
| Dimerization: |
| HOMODIMER INFORMATION |
There is experimental evidence for homo-dimerization
|
METHOD |
Bioluminescence Resonance Energy Transfer (BRET)
|
REFERENCES |
12554793
|
| HETERODIMER INFORMATION |
Forms functional heterodimers with V2 Receptors
|
METHOD |
Bioluminescence Resonance Energy Transfer (BRET)
|
REFERENCES |
12554793
|
| HETERODIMER INFORMATION |
Forms functional heterodimers with V1A Receptors
|
METHOD |
Bioluminescence Resonance Energy Transfer (BRET)
|
REFERENCES |
12554793
|
| Coupling with G-proteins: |
| Family:Gi/o |
REFERENCES: | 1313946 | | 1 | GPR0026 | Galpha-o-Rattus norvegicus | | 2 | GPR0111 | Galpha-i3-Rattus norvegicus | | 3 | GPR0221 | Galpha-i1-Rattus norvegicus | | 4 | GPR0229 | Galpha-i2-Rattus norvegicus | | Family:Gq/11 |
REFERENCES: | 1313946 | | 5 | GPR0032 | Galpha-11-Rattus norvegicus | | 6 | GPR0242 | Galpha-q-Rattus norvegicus |
|
biol.uoa.gr
for comments, corrections and
data (sequence) submission.
