gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::GPCR View
Entry 1 of 1 :: GPCR2511 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY TACHYKININ RECEPTOR
SUBFAMILY NK2

Cross References:
UniProt P16610 EMBL M31838
InterPro IPR000276 | IPR001681 | IPR000913 GPCRDB nk2r_rat
GENEID 25007
PRINTS PR00237 | PR01025 | PR00244 PFAM PF00001

Details:
NAME TACHYKININ RECEPTOR_NK2_Rattus norvegicus
DESCRIPTION Substance-K receptor (SKR) (Neurokinin A receptor) (NK-2 receptor)(NK-2R) (Tachykinin receptor 2).
SPECIES Rattus norvegicus COMMON NAME Rat NCBI Taxonomy 10116
GENE Tacr2 | Tac2r
SEQUENCE
MGTRAIVSDANILSGLESNATGVTAFSMPGWQLALWATAYLALVLVAVTGNATVIWIILA
HERMRTVTNYFIINLALADLCMAAFNATFNFIYASHNIWYFGRAFCYFQNLFPITAMFVS
IYSMTAIAADRYMAIVHPFQPRLSAPSTKAIIAGIWLVALALASPQCFYSTITVDEGATK
CVVAWPNDNGGKMLLLYHLVVFVLIYFLPLLVMFGAYSVIGLTLWKRAVPRHQAHGANLR
HLQAKKKFVKAMVLVVLTFAICWLPYHLYFILGTFQEDIYYHKFIQQVYLALFWLAMSST
MYNPIIYCCLNHRFRSGFRLAFRCCPWVTPTEEDRLELTHTPSLSRRVNRCHTKETLFMT
GDMTHSEATNGQVGSPQDGEPAGPICKAQA
FRAGMENT NO

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Coupling with G-proteins:
Family:Gq/11 REFERENCES:1370820
1GPR0032Galpha-11-Rattus norvegicus
2GPR0242Galpha-q-Rattus norvegicus
Family:Gs REFERENCES:1370820
3GPR0124Galpha-s-Rattus norvegicus-2
4GPR0392Galpha-s-Rattus norvegicus-1


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athina University of Athens
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Biophysics
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