| Details: |
| NAME |
SOMATOSTATIN RECEPTOR_SST5_Rattus norvegicus |
| DESCRIPTION |
Somatostatin receptor type 5 (SS5R). |
| SPECIES |
Rattus norvegicus |
COMMON NAME |
Rat |
NCBI Taxonomy |
10116 |
| GENE |
Sstr5 |
| SEQUENCE |
MEPLSLASTPSWNASAASSGNHNWSLVGSASPMGARAVLVPVLYLLVCTVGLSGNTLVIY
VVLRHAKMKTVTNVYILNLAVADVLFMLGLPFLATQNAVVSYWPFGSFLCRLVMTLDGIN
QFTSIFCLMVMSVDRYLAVVHPLRSARWRRPRVAKMASAAVWVFSLLMSLPLLVFADVQE
GWGTCNLSWPEPVGLWGAAFITYTSVLGFFGPLLVICLCYLLIVVKVKAAGMRVGSSRRR
RSEPKVTRMVVVVVLVFVGCWLPFFIVNIVNLAFTLPEEPTSAGLYFFVVVLSYANSCAN
PLLYGFLSDNFRQSFRKVLCLRRGYGMEDADAIEPRPDKSGRPQATLPTRSCEANGLMQT
SRI
|
FRAGMENT |
NO
|
|
|
|
|
Homepage
|
| Dimerization: |
| HOMODIMER INFORMATION |
There is experimental evidence for homo-dimerization
|
METHOD |
Immunoprecipitation, Fluorescence Resonance Energy Transfer (FRET)
|
REFERENCES |
10713101
|
| HETERODIMER INFORMATION |
Forms heterodimer with SST1 Receptor. Dimerization allows internalization of SST1 Receptor
|
METHOD |
Photobleaching Fluorescence Resonance Energy Transfer (FRET)
|
REFERENCES |
10713101
|
| HETERODIMER INFORMATION |
Forms heterodimer with Dopamine Receptor D2. Dimerization results in increased ligand binding affnity and enhanced signalling
|
METHOD |
Photobleaching Fluorescence Resonance Energy Transfer (FRET)
|
REFERENCES |
10753124
|
| Coupling with G-proteins: |
| Family:Gi/o |
REFERENCES: | 8373420 | | 1 | GPR0026 | Galpha-o-Rattus norvegicus | | 2 | GPR0111 | Galpha-i3-Rattus norvegicus | | 3 | GPR0221 | Galpha-i1-Rattus norvegicus | | 4 | GPR0229 | Galpha-i2-Rattus norvegicus |
|
biol.uoa.gr
for comments, corrections and
data (sequence) submission.
