gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0246 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY ADRENOCEPTOR (A2-ADRENOCEPTOR)
SUBFAMILY A2B(Adrenoceptor)

Cross References:
UniProt Q60475 EMBL U25723
InterPro IPR015695 | IPR000207 | IPR002233 | IPR000276 GPCRDB ada2b_cavpo
PRINTS PR01103 | PR00559 | PR00237 PFAM PF00001

Details:
NAME ADRENOCEPTOR (A2-ADRENOCEPTOR)_A2B(Adrenoceptor)_Cavia porcellus-2
DESCRIPTION Alpha-2B adrenergic receptor (Alpha-2B adrenoceptor) (Alpha-2Badrenoreceptor).
SPECIES Cavia porcellus COMMON NAME Guinea pig NCBI Taxonomy 10141
GENE ADRA2B
SEQUENCE
MDHQEPYSVQATAAIAAVITFLILFTIFGNALVILAVLTSRSLPAPQNLFLVSLAAADIL
VATLIIPFSLANELLGYWYFWRTWCEVYLALDVLFCTSSIVHLCAISLDRYWAVSRALEY
NSKRTPRRIKCIILTVWLIAAVISLPPLIYKGDQGPSPRGPQCKINQEAWYILASSIGSF
FAPCLIMILVYLRIYLIAKRSHRRGPRAKGGPGEGESKESRPSPGGAPASAKVPPLASPL
SSTGEANGHPKPTGEKEEGETSEDPGARTLPPSWAALPTSGQGQKKAVVLAPAEEEAEEE
EEEEGDECEPQAAPGLPASMCSPSLQQPQGSRVLATLRGQVLLGRGVGAVDGQWWRRRTQ
MTREKRFTFVLAVVIGVFVLCWFPFFFTYSLGAICPQHCKVPHGLFQFFFWIGYCNSSLN
PVIYTIFNQDFRRAFRRILCRQWTQTAW
FRAGMENT NO

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Scaffold:
TYPE 15-3-3 ksi REFERENCES 10224112
TYPE GASP( GPCR associated sorting protein) REFERENCES 12142540
TYPE Spinophilin/neurabin II REFERENCES 11154706

Coupling with G-proteins:
Family:Gi/o REFERENCES:2164221
1GPR0107Galpha-i3-Cavia porcellus
2GPR0216Galpha-i1-Cavia porcellus
3GPR0224Galpha-i2-Cavia porcellus


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athina University of Athens
Faculty of Biology
Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory