gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::GPCR View
Entry 1 of 1 :: GPCR2410 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY PLATELET ACTIVATING FACTOR (PAF) RECEPTOR
SUBFAMILY PLATELET ACTIVATING FACTOR (PAF) RECEPTOR

Cross References:
UniProt P21556 EMBL X56736
InterPro IPR000276 | IPR002282 GPCRDB ptafr_cavpo
PRINTS PR00237 | PR01153 PFAM PF00001

Details:
NAME PLATELET ACTIVATING FACTOR (PAF) RECEPTOR_PLATELET ACTIVATING FACTOR (PAF) RECEPTOR_Cavia porcellus
DESCRIPTION Platelet-activating factor receptor (PAF-R).
SPECIES Cavia porcellus COMMON NAME Guinea pig NCBI Taxonomy 10141
GENE PTAFR
SEQUENCE
MELNSSSRVDSEFRYTLFPIVYSIIFVLGIIANGYVLWVFARLYPSKKLNEIKIFMVNLT
VADLLFLITLPLWIVYYSNQGNWFLPKFLCNLAGCLFFINTYCSVAFLGVITYNRFQAVK
YPIKTAQATTRKRGIALSLVIWVAIVAAASYFLVMDSTNVVSNKAGSGNITRCFEHYEKG
SKPVLIIHICIVLGFFIVFLLILFCNLVIIHTLLRQPVKQQRNAEVRRRALWMVCTVLAV
FVICFVPHHMVQLPWTLAELGMWPSSNHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKF
RKHLSEKLNIMRSSQKCSRVTTDTGTEMAIPINHTPVNPIKN
FRAGMENT NO

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Dimerization:
HOMODIMER INFORMATION There is experimental evidence for homo-dimerization METHOD Immunoprecipitation REFERENCES 7929127

Coupling with G-proteins:
Family:Gi/o REFERENCES:7876256
1GPR0107Galpha-i3-Cavia porcellus
2GPR0216Galpha-i1-Cavia porcellus
3GPR0224Galpha-i2-Cavia porcellus


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athina University of Athens
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Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory