gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::GPCR View
Entry 1 of 1 :: GPCR2384 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY P2Y RECEPTOR
SUBFAMILY P2Y12

Cross References:
UniProt Q13304 | Q8N5S7 | Q9UDZ6 | Q9UE21 EMBL U33447 | Y12546 | Z94154 | Z94155 | BC031653 | BC039595
InterPro IPR000276 | IPR002286 GPCRDB gpr17_human
GENEID 2840 MIM 603071
PRINTS PR00237 | PR01157 PFAM PF00001

Details:
NAME P2Y RECEPTOR_P2Y12_Homo sapiens-2
DESCRIPTION Uracil nucleotide/cysteinyl leukotriene receptor (UDP/CysLT receptor)(G-protein coupled receptor 17) (P2Y-like receptor) (R12).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE GPR17
SEQUENCE
MSKRSWWAGSRKPPREMLKLSGSDSSQSMNGLEVAPPGLITNFSLATAEQCGQETPLENM
LFASFYLLDFILALVGNTLALWLFIRDHKSGTPANVFLMHLAVADLSCVLVLPTRLVYHF
SGNHWPFGEIACRLTGFLFYLNMYASIYFLTCISADRFLAIVHPVKSLKLRRPLYAHLAC
AFLWVVVAVAMAPLLVSPQTVQTNHTVVCLQLYREKASHHALVSLAVAFTFPFITTVTCY
LLIIRSLRQGLRVEKRLKTKAVRMIAIVLAIFLVCFVPYHVNRSVYVLHYRSHGASCATQ
RILALANRITSCLTSLNGALDPIMYFFVAEKFRHALCNLLCGKRLKGPPPSFEGKTNESS
LSAKSEL
FRAGMENT NO

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Coupling with G-proteins:
Family:Gi/o REFERENCES:11196645
1GPR0020Galpha-o1-Homo sapiens
2GPR0109Galpha-i3-Homo sapiens
3GPR0218Galpha-i1-Homo sapiens-1
4GPR0226Galpha-i2-Homo sapiens-2
5GPR0261Galpha-i1-Homo sapiens-2
6GPR0334Galpha-o-Homo sapiens
7GPR0365Galpha-i2-Homo sapiens-1


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athina University of Athens
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Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory