| Details: |
| NAME |
OPIOID AND OPIOID-LIKE RECEPTOR_KAPPA OPIOID PEPTIDE (KOR)_Cavia porcellus |
| DESCRIPTION |
Kappa-type opioid receptor (KOR-1). |
| SPECIES |
Cavia porcellus |
COMMON NAME |
Guinea pig |
NCBI Taxonomy |
10141 |
| GENE |
OPRK1 |
| SEQUENCE |
MGRRRQGPAQPASELPARNACLLPNGSAWLPGWAEPDGNGSAGPQDEQLEPAHISPAIPV
IITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYL
MNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINI
CIWLLSSSVGISAIILGGTKVREDVDIIECSLQFPDDDYSWWDLFMKICVFVFAFVIPVL
IIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFIICWTPIHIFILVEALG
STSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPIKMRMERQSTSRV
RNTVQDPAYMRNVDGVNKPV
|
FRAGMENT |
NO
|
|
|
|
|
Homepage
|
| Dimerization: |
| HOMODIMER INFORMATION |
There is experimental evidence for homo-dimerization
|
METHOD |
Immunoprecipitation
|
REFERENCES |
10385123
|
| HETERODIMER INFORMATION |
Forms heterodimers with delta Opioid Peptide Receptor. Dimerization results in altered ligand binding, potentiated signalling and altered internalization
|
METHOD |
Immunoprecipitation
|
REFERENCES |
10385123
|
| HETERODIMER INFORMATION |
Forms heterodimers with B2 Adrenoceptors. Heterodimerization results in altered internalization and MAPK signalling
|
METHOD |
Immunoprecipitation
|
REFERENCES |
11134510
|
| Scaffold: |
| TYPE |
NHERF1( Na+/H+ exchange regulatory factor) /EBP50( ezrin-radixin-moesin binding phosphoprotein 50-kD protein)
|
REFERENCES |
12004055
|
| Coupling with G-proteins: |
| Family:Gi/o |
REFERENCES: | 7624359 | | 1 | GPR0107 | Galpha-i3-Cavia porcellus | | 2 | GPR0216 | Galpha-i1-Cavia porcellus | | 3 | GPR0224 | Galpha-i2-Cavia porcellus |
|
biol.uoa.gr
for comments, corrections and
data (sequence) submission.
