| Details: |
| NAME |
ACETYLCHOLINE RECEPTOR (MUSCARINIC)_M3_Pongo pygmaeus |
| DESCRIPTION |
Muscarinic acetylcholine receptor M3. |
| SPECIES |
Pongo pygmaeus |
COMMON NAME |
Orangutan |
NCBI Taxonomy |
9600 |
| GENE |
CHRM3 |
| SEQUENCE |
MTLHSNSTTSPLFPNISSSWIHSPSDAGLPRGTVTHFGSYNVSRAAGNFSSPNGPTDDPL
GGHTVWQVVFIAFLTGILALVTIIGNILVIVSFKVNKQLKTVNNYFLLSLACADLIIGVI
SMNLFTTYIIMNRWALGNLACDLWLAIDYVASNASVMNLLVISFDRYFSITRPLTYRAKR
TTKRAGVMIGLAWVISFVLWAPAILFWQYFVGKRTVPPGECFIQFLSEPTITFGTAIAAF
YMPVTIMTILYWRIYKETEKRTKELAGLQASGTEAETENFVHPTGSSRSCSSYELQQQSM
KRANRRKYGRCHFWFTTKSWKPSSEQMDQDHSSSDSWNNNDAAASLENSASSDEEDIGSE
TRAIYSIVLKLPGHSTILNSTKLPSSDNLQVPEEELGMVDLERKANKLQAQKSVDDGGSF
PKSFSKLPIQLESAVDTAKTADVNSSVGKTTATLPLSFKEATLAKRFALKTRSQITKRKR
MSLVKEKKAAQTLSAILLAFIITWTPYNIMVLVNTFCDSCIPKTFWNLGYWLCYINSTVN
PVCYALCNKTFRTTFKMLLLCQCDKKKRRKQQYQQRQSVIFHKRAPEQAL
|
FRAGMENT |
NO
|
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|
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|
Homepage
|
| Dimerization: |
| HOMODIMER INFORMATION |
There is experimental evidence for homo-dimerization
|
METHOD |
Immunoprecipitation
|
REFERENCES |
10383466
|
| HETERODIMER INFORMATION |
Forms heterodimers with Muscarinic M2 Receptors. Heterodimerization results in altered internalization of the receptors
|
METHOD |
Chimeric receptor reconstitution studies
|
REFERENCES |
10490911
|
| Coupling with G-proteins: |
| No information |
|
biol.uoa.gr
for comments, corrections and
data (sequence) submission.
