gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0013 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY 5-HYDROXYTRYPTAMINE RECEPTOR
SUBFAMILY 5-HT-1A

Cross References:
UniProt Q9N296 EMBL AB041406
InterPro IPR000610 | IPR002231 | IPR000276 GPCRDB 5ht1a_ponpy
PRINTS PR00512 | PR01101 | PR00237 PFAM PF00001

Details:
NAME 5-HYDROXYTRYPTAMINE RECEPTOR_5-HT-1A_Pongo pygmaeus
DESCRIPTION 5-hydroxytryptamine receptor 1A (5-HT-1A) (Serotonin receptor 1A) (5-HT1A).
SPECIES Pongo pygmaeus COMMON NAME Orangutan NCBI Taxonomy 9600
GENE HTR1A
SEQUENCE
MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTFSYQVITSLLLGTLIFCAVLGNACVVAA
IALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCC
TSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPED
RSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADT
HHGASPAPQPKKSVNGESGSRNWRLGVESKAGGGLCANGAVRQGDDGAALEVIEVHRVGN
SKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLP
FFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFC
RQ
FRAGMENT NO

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Coupling with G-proteins:
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athina University of Athens
Faculty of Biology
Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory