gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::GPCR View
Entry 1 of 1 :: GPCR1253 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY NEUROPEPTIDE Y RECEPTOR
SUBFAMILY Y2

Cross References:
UniProt Q9Z2D5 EMBL AF072821
InterPro IPR000276 | IPR001358 | IPR000611 GPCRDB npy2r_cavpo
PRINTS PR00237 | PR01014 | PR01012 PFAM PF00001

Details:
NAME NEUROPEPTIDE Y RECEPTOR_Y2_Cavia porcellus
DESCRIPTION Neuropeptide Y receptor type 2 (NPY2-R) (NPY-Y2 receptor).
SPECIES Cavia porcellus COMMON NAME Guinea pig NCBI Taxonomy 10141
GENE NPY2R
SEQUENCE
MGPIGTEADENQTVEEIKVEPYGPGHTTPRGELAPDPEPELIDSTKLTEVRVVLILAYCS
IILLGVVGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMG
PVLCHLVPYAQGLAVQVSTVTLTVIALDRHRCIVYHLDSKISKQNSFLIIGLAWGISALL
ASPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISVSY
VRIWSKLKNHVSPGAANDHYHQRRQKTTKMLVFVVVVFAVSWLPLHAFQLAVDIDSQVLD
LKEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRCQQRLDAIQSEVCVTGKA
KTNVEVEKNHGAADSAEATNV
FRAGMENT NO

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Dimerization:
HOMODIMER INFORMATION There is experimental evidence for homo-dimerization METHOD Fluorescence Resonance Energy Transfer (FRET) REFERENCES 12524448

Coupling with G-proteins:
Family:Gi/o REFERENCES:7559383
1GPR0107Galpha-i3-Cavia porcellus
2GPR0216Galpha-i1-Cavia porcellus
3GPR0224Galpha-i2-Cavia porcellus


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athina University of Athens
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