gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::GPCR View
Entry 1 of 1 :: GPCR1222 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY MELATONIN RECEPTOR
SUBFAMILY MT1

Cross References:
UniProt O02781 EMBL U73326
InterPro IPR000276 | IPR002278 | IPR000025 GPCRDB mtr1a_pig
PRINTS PR00237 | PR01149 | PR00857 PFAM PF00001

Details:
NAME MELATONIN RECEPTOR_MT1_Sus scrofa
DESCRIPTION Melatonin receptor type 1A .
SPECIES Sus scrofa COMMON NAME Pig NCBI Taxonomy 9823
GENE MTNR1A
SEQUENCE
YCYICHSLKYDRWYSNRNSLCCVFLICVLTLVAIVPNLCMGTLQYDPRIYSCTFAQSVSS
AYTIAVVVFHFLVPMVIVIFRYLRIWVLVLQIRWRAKPENNPRLKPQDFRNFVTMFVVFV
LFAICWAPLNFIGLAVASDPASMAPRIPEWLFVA
FRAGMENT YES

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Dimerization:
HOMODIMER INFORMATION There is experimental evidence for homo-dimerization METHOD Immunoprecipitation, Bioluminescence Resonance Energy Transfer (BRET) REFERENCES 11940583
HETERODIMER INFORMATION Forms heterodimers with Melatonin MT2 Receptors. METHOD Immunoprecipitation, Bioluminescence Resonance Energy Transfer (BRET) REFERENCES 11940583

Coupling with G-proteins:
No information


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athina University of Athens
Faculty of Biology
Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory