gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::GPCR View
Entry 1 of 1 :: GPCR1043 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY LYSOPHOSPHOLIPID RECEPTOR
SUBFAMILY S1P1

Cross References:
UniProt P48303 | Q4V7F6 EMBL U10303 | BC097938
InterPro IPR000987 | IPR002277 | IPR000276 | IPR004061 GPCRDB edg1_rat
GENEID 29733
PRINTS PR00642 | PR01148 | PR00237 | PR01523 PFAM PF00001

Details:
NAME LYSOPHOSPHOLIPID RECEPTOR_S1P1_Rattus norvegicus-3
DESCRIPTION Sphingosine 1-phosphate receptor Edg-1 (Sphingosine 1-phosphatereceptor 1) (S1P1).
SPECIES Rattus norvegicus COMMON NAME Rat NCBI Taxonomy 10116
GENE Edg1
SEQUENCE
MVSSTSIPVVKALRSQVSDYGNYDIIVRHYNYTGKLNIGVEKDHGIKLTSVVFILICCLI
ILENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYTANLLLSGATTYKLTPAQWFL
REGSMFVALSASVFSLLAIAIERYITMLKMKLHNGSNSSRSFLLISACWVISLILGGLPI
MGWNCISSLSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILYCRIYSLVRTRSRRLTFRK
NISKASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLDVGCKAKTCDILYKAEYFLVL
AVLNSGTNPIIYTLTNKEMRRAFIRIISCCKCPNGDSAGKFKRPIIPGMEFSRSKSDNSS
HPQKDDGDNPETIMSSGNVNSSS
FRAGMENT NO

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Coupling with G-proteins:
Family:Gi/o REFERENCES:9488656
1GPR0026Galpha-o-Rattus norvegicus
2GPR0111Galpha-i3-Rattus norvegicus
3GPR0221Galpha-i1-Rattus norvegicus
4GPR0229Galpha-i2-Rattus norvegicus


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athina University of Athens
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Biophysics
& Bioinformatics
Laboratory