gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::Effector View
Entry 1 of 1 :: EFF0091 ::
FAMILY Ion channels
SUBFAMILY ATP-sensitive inward rectifier potassium channels
TYPE ATP-sensitive inward rectifier potassium channel 12

Cross References:
UniProt P52187 | Q9QYF2 EMBL X80417 | AB035889
InterPro IPR001838 | IPR003272 | IPR013521 | IPR013518 | IPR013673
PRODOM PD001103
PRINTS PR01325 | PR01320 PFAM PF01007 | PF08466

Details:
NAME ATP-sensitive inward rectifier potassium channel-12-Mus musculus-2
DESCRIPTION ATP-sensitive inward rectifier potassium channel 12 (Potassiumchannel, inwardly rectifying subfamily J member 12) (Inward rectifierK(+) channel Kir2.2) (IRK2).
SPECIES Mus musculus COMMON NAME Mouse NCBI Taxonomy 10090
GENE Kcnj12 | Irk2
SEQUENCE 
MTAASRANPYSIVSSEEDGLHLVTMSGANGFGNGKVHTRRRCRNRFVKKNGQCNIEFANM
DEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGIIFWVIAVAHGDLEPAEGRGR
TPCVLQVHGFMAAFLFSIETQTTIGYGLRCVTEECPVAVFMVVAQSIVGCIIDSFMNGAI
MAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPRVTEE
GEYIPLDQIDIDVGF
 FRAGMENT NO
FUNCTION Probably participates in establishing action potentials waveform and excitability of neuronal and muscle tissues
Interacting with G-proteins:
Family:Gbeta REFERENCES:15251227 | 10990455
1GPR0148Gbeta-1-Mus musculus
2GPR0156Gbeta-2-Mus musculus
3GPR0161Gbeta-3-Mus musculus
4GPR0165Gbeta-4-Mus musculus
5GPR0168Gbeta-5-Mus musculus-2
6GPR0291unclassified_Gbeta-Mus musculus-1
7GPR0318unclassified_Gbeta-Mus musculus-2
8GPR0376Gbeta-5-Mus musculus-3
9GPR0377Gbeta-5-Mus musculus-1
Family:Ggamma REFERENCES:15251227 | 10990455
10GPR0178Ggamma-t1-Mus musculus
11GPR0181Ggamma-2-Mus musculus
12GPR0184Ggamma-3-Mus musculus
13GPR0186Ggamma-4-Mus musculus
14GPR0189Ggamma-5-Mus musculus
15GPR0193Ggamma-7-Mus musculus
16GPR0196Ggamma-8-Mus musculus-2
17GPR0200Ggamma-11-Mus musculus
18GPR0204Ggamma-12-Mus musculus
19GPR0206Ggamma-13-Mus musculus
20GPR0211Ggamma-8-Mus musculus-1
21GPR0349Ggamma-1-Mus musculus
22GPR0379Ggamma-10-Mus musculus

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athina University of Athens
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 Dept. of Cell Biology and Biophysics
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