gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::Effector View
Entry 1 of 1 :: EFF0087 ::
FAMILY Ion channels
SUBFAMILY ATP-sensitive inward rectifier potassium channels
TYPE ATP-sensitive inward rectifier potassium channel 12

Cross References:
UniProt Q4TZY1 EMBL DQ023214
InterPro IPR001838 | IPR003272 | IPR013521 | IPR013518 | IPR013673
PRODOM PD001103
PRINTS PR01325 | PR01320 PFAM PF01007 | PF08466

Details:
NAME ATP-sensitive inward rectifier potassium channel-12-Bos taurus
DESCRIPTION ATP-sensitive inward rectifier potassium channel 12 (Potassiumchannel, inwardly rectifying subfamily J member 12).
SPECIES Bos taurus COMMON NAME Bovine NCBI Taxonomy 9913
GENE KCNJ12
SEQUENCE 
MTASGRTNPYSIVSSEEDGLHLVTMSGANGFGNGKVHTRRRCRNRFVKKNGQCNIEFANM
DEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGVIFWVIAVAHGDLEPAEAHGR
TPCVLQVHGFMAAFLFSIETQTTIGYGLRCVTEECPVAVFMVVAQSIVGCIIDSFMIGAI
MAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPRVTEE
GEYIPLDQIDIDVGF
 FRAGMENT NO
FUNCTION Probably participates in establishing action potentials waveform and excitability of neuronal and muscle tissues
Interacting with G-proteins:
Family:Gbeta REFERENCES:15251227 | 10990455
1GPR0145Gbeta-1-Bos taurus
2GPR0152Gbeta-2-Bos taurus
Family:Ggamma REFERENCES:15251227 | 10990455
3GPR0174Ggamma-t1-Bos taurus
4GPR0180Ggamma-2-Bos taurus
5GPR0182Ggamma-3-Bos taurus
6GPR0187Ggamma-5-Bos taurus
7GPR0191Ggamma-7-Bos taurus
8GPR0202Ggamma-12-Bos taurus
9GPR0209Ggamma-8-Bos taurus

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athina University of Athens
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 Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory