gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::Effector View
Entry 1 of 1 :: EFF0831 ::
FAMILY SHC transforming proteins
SUBFAMILY SHC transforming proteins
TYPE SHC transforming protein 1

Cross References:
UniProt P98083 | Q3U2Q7 | Q8BFY3 | Q8K4C6 | Q8K4C7 EMBL U46956 | U15784 | AK049357 | AK155158 | BC036172 | AF455140 | AF455140
InterPro IPR011993 | IPR006019 | IPR006020 | IPR000980
PRODOM PD000093 GENEID 20416
PRINTS PR00401 | PR00629 PFAM PF00640 | PF00017

Details:
NAME SHC transforming protein-1-Mus musculus
DESCRIPTION SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2domain-containing-transforming protein C1).
SPECIES Mus musculus COMMON NAME Mouse NCBI Taxonomy 10090
GENE Shc1 | Shc | ShcA
SEQUENCE 
MDLLPPKPKYNPLRNESLSSLEEGASGSTPPEELPSPSASSLGPILPPLPGDDSPTTLCS
FFPRMSNLKLANPAGGRLGPKGEPGKAAEDGEGSAGAALRDSGLLPLLQDMNKLSGGGGR
RTRVEGGQLGGEEWTRHGSFVNKPTRGWLHPNDKVMGPGVSYLVRYMGCVEVLQSMRALD
FNTRTQVTREAISLVCEAVPGAKGATRRRKPCSRPLSSILGRSNLKFAGMPITLTVSTSS
LNLMAADCKQIIANH
 FRAGMENT NO
FUNCTION Signaling adapter that couples activated growth factors receptors to signaling pathway
Interacting with G-proteins:
Family:Gbeta REFERENCES:15251227 | 14671004 | 7568118
1GPR0148Gbeta-1-Mus musculus
2GPR0156Gbeta-2-Mus musculus
3GPR0161Gbeta-3-Mus musculus
4GPR0165Gbeta-4-Mus musculus
5GPR0168Gbeta-5-Mus musculus-2
6GPR0291unclassified_Gbeta-Mus musculus-1
7GPR0318unclassified_Gbeta-Mus musculus-2
8GPR0376Gbeta-5-Mus musculus-3
9GPR0377Gbeta-5-Mus musculus-1
Family:Ggamma REFERENCES:15251227 | 14671004 | 7568118
10GPR0178Ggamma-t1-Mus musculus
11GPR0181Ggamma-2-Mus musculus
12GPR0184Ggamma-3-Mus musculus
13GPR0186Ggamma-4-Mus musculus
14GPR0189Ggamma-5-Mus musculus
15GPR0193Ggamma-7-Mus musculus
16GPR0196Ggamma-8-Mus musculus-2
17GPR0200Ggamma-11-Mus musculus
18GPR0204Ggamma-12-Mus musculus
19GPR0206Ggamma-13-Mus musculus
20GPR0211Ggamma-8-Mus musculus-1
21GPR0349Ggamma-1-Mus musculus
22GPR0379Ggamma-10-Mus musculus

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athina University of Athens
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 Dept. of Cell Biology and Biophysics
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& Bioinformatics
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