gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::Effector View
Entry 1 of 1 :: EFF0694 ::
FAMILY GTPase activating proteins
SUBFAMILY Ras GTPase activating proteins
TYPE Ras GTPase activating protein 2

Cross References:
UniProt P58069 EMBL AB056433
InterPro IPR001562 | IPR000008 | IPR001849 | IPR011993 | IPR001936
PRINTS PR00360 | PR00402 PFAM PF00779 | PF00168 | PF00169 | PF00616

Details:
NAME Ras GTPase activating protein-2-Mus musculus
DESCRIPTION Ras GTPase-activating protein 2 (GAP1m).
SPECIES Mus musculus COMMON NAME Mouse NCBI Taxonomy 10090
GENE Rasa2
SEQUENCE
MAAAAPAAAAASPEAPAVSGSADPETGDEDSREVRVLQSLRGRIYEAKNLLPYLGPNKMR
DCFCTINLDQEEVYRTQVVEKSLSPYFSEEFYFEIPRTFQYLSFYVYDKNVLQRDLRIGK
VAIKKEDLCSHSGKETWFSLQPIDSNSEVQGKVHLELRLNELITENGTVCQQLVVHIKAC
HGLPLINGQSCDPYATVSLVGPSRNDQKKTKVKKKTSNPQFNEVFYFEVTRSSSYSRKSQ
FQVEEEDIEKLEIRI
FRAGMENT NO
FUNCTION Inhibitory regulator of the Ras-cyclic AMP pathway
Interacting with G-proteins:
Family:G12/13 REFERENCES:15251227
1GPR0035Galpha-12-Mus musculus
2GPR0038Galpha-13-Mus musculus-2
3GPR0323Galpha-13-Mus musculus-3
4GPR0380Galpha-13-Mus musculus-1


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athina University of Athens
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Dept. of Cell Biology and Biophysics
Biophysics
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Laboratory