gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::Effector View
Entry 1 of 1 :: EFF0687 ::
FAMILY Ser Thr protein kinases
SUBFAMILY RAF protein kinases
TYPE Raf1 protein kinase

Cross References:
UniProt Q99N57 | Q91WH1 EMBL AB057663 | BC015273
InterPro IPR002219 | IPR000719 | IPR003116 | IPR008271
PRODOM PD000001 GENEID 110157
PRINTS PR00008 PFAM PF00130 | PF00069 | PF02196

Details:
NAME Raf1 protein kinase-Mus musculus-5
DESCRIPTION RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf-1) (C-RAF) (cRaf).
SPECIES Mus musculus COMMON NAME Mouse NCBI Taxonomy 10090
GENE Raf1 | Craf
SEQUENCE
MEHIQGAWKTISNGFGLKDAVFDGSSCISPTIVQQFGYQRRASDDGKLTDSSKTSNTIRV
FLPNKQRTVVNVRNGMSLHDCLMKALKVRGLQPECCAVFRLLQEHKGKKARLDWNTDAAS
LIGEELQVDFLDHVPLTTHNFARKTFLKLAFCDICQKFLLNGFRCQTCGYKFHEHCSTKV
PTMCVDWSNIRQLLLFPNSTVGDSGVPAPPSFPMRRMRESVSRMPASSQHRYSTPHAFTF
NTSSPSSEGSLSQRQ
FRAGMENT NO
FUNCTION Involved in the transduction of mitogenic signals froms the cell membrane to the nucleus
Interacting with G-proteins:
Family:Gbeta REFERENCES:15251227
1GPR0148Gbeta-1-Mus musculus
2GPR0156Gbeta-2-Mus musculus
3GPR0161Gbeta-3-Mus musculus
4GPR0165Gbeta-4-Mus musculus
5GPR0168Gbeta-5-Mus musculus-2
6GPR0291unclassified_Gbeta-Mus musculus-1
7GPR0318unclassified_Gbeta-Mus musculus-2
8GPR0376Gbeta-5-Mus musculus-3
9GPR0377Gbeta-5-Mus musculus-1
Family:Ggamma REFERENCES:15251227
10GPR0178Ggamma-t1-Mus musculus
11GPR0181Ggamma-2-Mus musculus
12GPR0184Ggamma-3-Mus musculus
13GPR0186Ggamma-4-Mus musculus
14GPR0189Ggamma-5-Mus musculus
15GPR0193Ggamma-7-Mus musculus
16GPR0196Ggamma-8-Mus musculus-2
17GPR0200Ggamma-11-Mus musculus
18GPR0204Ggamma-12-Mus musculus
19GPR0206Ggamma-13-Mus musculus
20GPR0211Ggamma-8-Mus musculus-1
21GPR0349Ggamma-1-Mus musculus
22GPR0379Ggamma-10-Mus musculus


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athina University of Athens
Faculty of Biology
Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory