gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::Effector View
Entry 1 of 1 :: EFF0411 ::
FAMILY Ion channels
SUBFAMILY Inwar rectifier K channels
TYPE Kir 3 2(GIRK2)

Cross References:
UniProt P49658 EMBL U21937
InterPro IPR001838 | IPR003275 | IPR013521 | IPR013518
PRODOM PD001103
PRINTS PR01328 | PR01320 PFAM PF01007

Details:
NAME Kir 3.2(GIRK2)-Mesocricetus auratus
DESCRIPTION G protein-activated inward rectifier potassium channel 2 (GIRK2)(Potassium channel, inwardly rectifying subfamily J member 6) (Inwardrectifier K(+) channel Kir3.2) (KATP-2).
SPECIES Mesocricetus auratus COMMON NAME Golden hamster NCBI Taxonomy 10036
GENE KCNJ6 | GIRK2 | KATP2 | KCNJ7
SEQUENCE
MTMAKLTESMTNVLEGDSMDQDVESPVAIHQPKLPKQARDDLPRHISRDRTKRKIQRYVR
KDGKCNVHHGNVRETYRYLTDILTTLVDLKWRFNLLIFVMVYTVTWLFFGMIWWLIAYIR
GDMDHVEDPSWTPCVTNLNGFVSAFLFSIETETTIGYGYRVITDKCPEGIILLLIQSVLG
SIVNAFMVGCMFVKISQPKKRAETLVFSTHAVISMRDGKLCLMFRVGDLRNSHIVEASIR
AKLIKSKQTSEGEFI
FRAGMENT NO
FUNCTION This potassium channel may be involved in the regulations of insulin secretion by glucose and/or neurotransmitters actings through G-protein-coupled receptors
Interacting with G-proteins:
Family:Gbeta REFERENCES:15251227 | 10944236 | 12661754
1GPR0288Gbeta-5-Mesocricetus auratus


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