gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::Effector View
Entry 1 of 1 :: EFF0377 ::
FAMILY Ser Thr protein kinases
SUBFAMILY G protein coupled receptor kinases
TYPE GRK6

Cross References:
UniProt O70293 | O70294 | O70295 EMBL AF040747 | AF040748 | AF040749 | AF040754 | Y17967 | Y17967 | Y15798 | Y15799
InterPro IPR000239 | IPR000961 | IPR000719 | IPR000342 | IPR008271 | IPR002290
PRODOM PD000001
PRINTS PR00717 PFAM PF00069 | PF00615

Details:
NAME GRK6-Mus musculus
DESCRIPTION G protein-coupled receptor kinase 6 (EC 2.7.11.16) (G protein-coupledreceptor kinase GRK6).
SPECIES Mus musculus COMMON NAME Mouse NCBI Taxonomy 10090
GENE Grk6 | Gprk6
SEQUENCE 
MELENIVANTVLLKAREGGGGNRKGKSKKWRQMLQFPHISQCEELRLSLERDYHSLCERQ
PIGRLLFREFCATRPELTRCTAFLDGVSEYEVTPDEKRKACGRRLMQNFLSHTGPDLIPE
VPRQLVSNCAQRLEQGPCKDLFQELTRLTHEYLSTAPFADYLDSIYFNRFLQWKWLERQP
VTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEK
VNSRFVVSLAYAYET
 FRAGMENT NO
FUNCTION Specifically phosphorylates the activated forms of Gs protein-coupled receptors (By similarity)
Interacting with G-proteins:
Family:Gq/11 REFERENCES:14654303
1GPR0044Galpha-15-Mus musculus

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athina University of Athens
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