gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::Effector View
Entry 1 of 1 :: EFF0372 ::
FAMILY Ser Thr protein kinases
SUBFAMILY G protein coupled receptor kinases
TYPE GRK5

Cross References:
UniProt P34947 EMBL L15388 | BC064506
InterPro IPR000239 | IPR000961 | IPR000719 | IPR000342 | IPR008271 | IPR002290
PRODOM PD000001 GENEID 2869 MIM 600870
PRINTS PR00717 PFAM PF00069 | PF00615

Details:
NAME GRK5-Homo sapiens
DESCRIPTION G protein-coupled receptor kinase 5 (EC 2.7.11.16) (G protein-coupledreceptor kinase GRK5).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE GRK5 | GPRK5
SEQUENCE
MELENIVANTVLLKAREGGGGKRKGKSKKWKEILKFPHISQCEDLRRTIDRDYCSLCDKQ
PIGRLLFRQFCETRPGLECYIQFLDSVAEYEVTPDEKLGEKGKEIMTKYLTPKSPVFIAQ
VGQDLVSQTEEKLLQKPCKELFSACAQSVHEYLRGEPFHEYLDSMFFDRFLQWKWLERQP
VTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKRLEKKRIKKRKGESMALNEKQILEK
VNSQFVVNLAYAYET
FRAGMENT NO
FUNCTION Specifically phosphorylates the activated forms of Gs protein-coupled receptors
Interacting with G-proteins:
No information


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athina University of Athens
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Biophysics
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