gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::Effector View
Entry 1 of 1 :: EFF0371 ::
FAMILY Ser Thr protein kinases
SUBFAMILY G protein coupled receptor kinases
TYPE GRK5

Cross References:
UniProt P43249 EMBL U01206
InterPro IPR000239 | IPR000961 | IPR000719 | IPR000342 | IPR008271 | IPR002290
PRODOM PD000001 GENEID 281801
PRINTS PR00717 PFAM PF00069 | PF00615

Details:
NAME GRK5-Bos taurus
DESCRIPTION G protein-coupled receptor kinase 5 (EC 2.7.11.16) (G protein-coupledreceptor kinase GRK5).
SPECIES Bos taurus COMMON NAME Bovine NCBI Taxonomy 9913
GENE GRK5 | GPRK5
SEQUENCE
MELENIVANTVLLKAREGGGGKRKGKSKKWKEILKFPHINQCEDLRRTIDRDYCSLCDKQ
PVGRLLFRQFCETRPGLESYIQFLDSVAEYEVTPDEKLGEKGKEIMTKYLTPKSPVFITQ
VGRDLVSQTEEKLLQKPCKELFSACVQSVHDYLRGEPFHEYLDSMYFDRFLQWKWLERQP
VTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKRLEKKRIKKRKGESMALNEKQILEK
VNSRFVVNLAYAYET
FRAGMENT NO
FUNCTION Specifically phosphorylates the activated forms of Gs protein-coupled receptors
Interacting with G-proteins:
No information


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athina University of Athens
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Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory