gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::Effector View
Entry 1 of 1 :: EFF0367 ::
FAMILY Ser Thr protein kinases
SUBFAMILY G protein coupled receptor kinases
TYPE GRK4

Cross References:
UniProt P70507 | P70508 EMBL X97568 | X97568
InterPro IPR000239 | IPR000961 | IPR000719 | IPR000342 | IPR008271 | IPR002290
PRODOM PD000001 GENEID 59077
PRINTS PR00717 PFAM PF00069 | PF00615

Details:
NAME GRK4-Rattus norvegicus
DESCRIPTION G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G protein-coupledreceptor kinase GRK4).
SPECIES Rattus norvegicus COMMON NAME Rat NCBI Taxonomy 10116
GENE Grk4 | Gprk2l
SEQUENCE 
MELENFMANTLLLKARQGFTKKTGRSKKWRELLKLPPVSMCSDLRHSIEKDFSSLCDQQP
IGRLLFRQFCNTKPDLKRCIEFLDAAAEYEVTIEEEQREFGLSIYSRFFKENSEVSLPQI
PPDLVKECKCNLKQSSPSQNVFQDCAGVIYKYLSEKPFEEYQESTYYNRFLQWKWLERRP
VTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKRILEK
LHSRFVVSLAYTYET
 FRAGMENT NO
FUNCTION Specifically phosphorylates the activated forms of Gs protein-coupled receptors
Interacting with G-proteins:
Family:Gq/11 REFERENCES:15251227 | 14654303
1GPR0032Galpha-11-Rattus norvegicus

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