gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::Effector View
Entry 1 of 1 :: EFF0339 ::
FAMILY Ezrin-radixin-moesin-binding phosphoproteins
SUBFAMILY Ezrin-radixin-moesin-binding phosphoproteins
TYPE EBP50/NHERF 1

Cross References:
UniProt Q9JJ19 EMBL AF154336
InterPro IPR015098 | IPR001478
GENEID 59114
PFAM PF09007 | PF00595

Details:
NAME EBP50/NHERF-1-Rattus norvegicus
DESCRIPTION Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+)exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor ofNa(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1)(Solute carrier family 9 isoform A3 regulatory fac
SPECIES Rattus norvegicus COMMON NAME Rat NCBI Taxonomy 10116
GENE Slc9a3r1 | Nherf
SEQUENCE
MSADAAAGEPLPRLCCLEKGPNGYGFHLHGEKGKVGQFIRLVEPGSPAEKSGLLAGDRLV
EVNGENVEKETHQQVVSRIRAALNAVRLLVVDPETDEQLKKLGVPIREELLRAQEKSEHT
EPPAAADTKKAGDQNEAEKSHLERCELRPRLCTMKKGPNGYGFNLHSDKSKPGQFIRAVD
PDSPAEASGLRAQDRIVEVNGVCMEGKQHGDVVSAIKAGGDEAKLLVVDKETDEFFKKCR
VTPSQEHLDGPLPEP
FRAGMENT NO
FUNCTION Scaffold protein that connects plasma membrane proteinss with members of the ezrin/moesin/radixin family and thereby helpss to link them to the actin cytoskeleton and to regulate theirs surface expression
Interacting with G-proteins:
Family:Gq/11 REFERENCES:16182515
1GPR0242Galpha-q-Rattus norvegicus


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