gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::Effector View
Entry 1 of 1 :: EFF0019 ::
FAMILY Cyclases
SUBFAMILY Adenylate cyclases
TYPE Adenylate cyclase 3

Cross References:
UniProt P21932 EMBL M55075
InterPro IPR001054
GENEID 64508
PFAM PF00211

Details:
NAME Adenylate cyclase-3-Rattus norvegicus
DESCRIPTION Adenylate cyclase type 3 (EC 4.6.1.1) (Adenylate cyclase type III)(ATP pyrophosphate-lyase 3) (Adenylyl cyclase 3) (AC-III) (AC3)(Adenylate cyclase, olfactive type).
SPECIES Rattus norvegicus COMMON NAME Rat NCBI Taxonomy 10116
GENE Adcy3
SEQUENCE
MTEDQGFSDPEYSAEYSAEYSVSLPSDPDRGVGRTHEISVRNSGSCLCLPRFMRLTFVPE
SLENLYQTYFKRQRHETLLVLVVFAALFDCYVVVMCAVVFSSDKLAPLMVAGVGLVLDII
LFVLCKKGLLPDRVSRKVVPYLLWLLITAQIFSYLGLNFSRAHAASDTVGWQAFFVFSFF
ITLPLSLSPIVIISVVSCVVHTLVLGVTVAQQQQDELEGMQLLREILANVFLYLCAIIVG
IMSYYMADRKHRKAF
FRAGMENT NO
FUNCTION Mediates odorant detection (possibly) via modulation ofs intracellular cAMP concentration
Interacting with G-proteins:
Family:Gs REFERENCES:15251227 | 15922020 | 14993377 | 11376933
1GPR0124Galpha-s-Rattus norvegicus-2
2GPR0392Galpha-s-Rattus norvegicus-1


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athina University of Athens
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Biophysics
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Laboratory